The PRICELESS SA (Priority Cost Effective Lessons for System Strengthening South Africa) initiative is hosted by Wits University School of Public Health in the Faculty of Health Sciences together with the SA Medical Research Council/ Wits Unit in Rural Public Health and Health Transitions Research. PRICELESS SA is a program to enable smart decisions about health investments in South Africa. The aim of the initiative is to generate and support the development of evidence-based information and tools to help determine how best to allocate existing scarce resources so that health systems work more effectively and efficiently